 Pangeenomes provide useful resources for evolutionary studies, functional genomics, and breeding of cultivated plants. Here, the authors report a new rice pangeenome including 73 Asian rice and two wild relatives, or as a Rufipagan and L. Pantata and reveal the prevalence and scale of large inversions across the pangeenome. This article was authored by Yongju, Chachou Yu, Demetro Chepotarov, and others.