 Hey everybody. I'm Dr. Jen Myers. I am a Neutrogenetic Specialist. I have focused my personal practice around Neutrogenetics alone. I'm also a scientist who studies nutritional pathways as well as genetics and how these two kind of coincide. So that's kind of what my topic is of course going to be about today is Neutrogenetics. And of course using genetics to optimize what we call our evolution based nutrition or how our nutrition has changed. We've got some really neat studies that we're currently working on that I'll be talking a bit about too. So just a disclaimer. The research discussed some of this is unpublished so I'm going to be giving everybody a little bit of insight as to what we've been doing lately. I'm also a scientific advisory board for Link Biosciences which does has a lot to do with genetics and DNA supplementation based off genetic variances and also euphoria science same kind of thing using DNA supplementation overlooking certain biochemical pathways of course. I do formulate for Sun Warrior. I put that on there because I had to learn what it was like to become a vegan. That was not fun needless to say. So it was interesting and actually one of the patients I'll discuss on here has a lot to do with his kind of evolutionary mismatch of him being a vegan and some of his genetic background. This is my clinical data. Things that I have seen within my practice as well as based on current and past scientific data and research. I think everybody knows this statement, right? Let thy food be thy medicine and thy medicine be thy food. We're looking at ancient wisdom with evolving and current modern nutrition as well as modern science bringing in the genetic component. It literally I think we're finally starting to realize that this famous statement should be taken quite seriously right? We're coming back to the basics in nutrition and science and kind of looking at to who we are as human beings and also Hippocrates said one man's food can be another man's poison and I have found this to be really true when looking at genetic variances and some of these patients is just because somebody can have let's say kombucha. There's another person that may not be able to have this because they have this particular variant the AOC1 gene where they can't break down these external histamines. So everybody thinks that oh I'm drinking kombucha I'm doing this good thing but then we're realizing that it's not going to be the same for everybody across the board. So some things we're going to be discussing today. The ecosystem of life in modern times what that means. Micro organisms and nutrients and how they coincide together. Genetics are necessary for life obviously. The conversation of nutrigenetics and how that's starting to evolve. Types of different genetic testing. I think this is an important part to bring up because everybody seems to think that all genetic testing is the same and that's actually not true. Unpublished data and research that we are currently working on. The biggest threat to our DNA and what that means and the evolution of present and future wellness. What we are doing as scientists and practitioners in the community to be able to help support our genetic variants our lifestyle and our nutritional supplementation. Modern day ecosystem who thinks there's a problem with that right. So we're looking at these different variables that are included in that. So with our social our social our environmental and our economic social of course meeting health our traditions our cultures things that we do within our personal lives as well our education and our learning systems our economic has a lot to do with the trade where are we getting these things from right our income how much money we make which should not be an accountable but it is marketing the things that people marketing and saying that you should take this because and everybody tends to believe it and also has to do with environmental right our climate and climate change that's happening that's a big it's topic biodiversity and how everything that we coincide together ourselves our micronutrients our microorganisms our soil quality which we know has been depleted it's not the same as it used to be and then of course it's going to list health health health health because that's super important when it comes to things like the quality of our water you know drinking tap water nowadays is this kind of we're all trying to filter and use water that's that's not as toxic I'm going to use that word our air quality as well you walk outside and take a deep breath and sometimes you think okay what in the world are those lines in the sky and what does that mean it all has to come back to our health as well so food production is also a big thing we're trying to produce more food to feed more people so that the quality of what they're using within our food is kind of decreasing and it's affecting our health so those are some things we're going to talk about that are involved in it the main influences I should say also going to speak about microorganisms what are microorganisms right so bacteria fungus viruses those are all included with these microorganisms and how they respond to the environment are we feeding them properly are we giving them enough nutrition to be able to survive and thrive and help us perform at a more optimal level so the microorganisms and nutrients right are we feeding them properly are we giving them the right nutrition and the right amount for us and how does this influence our our genetics our genetic makeup I just left a speech where he talked very much so about how genetics do not influence our health and and there is obviously definitely some some truth to that but what I'm going to talk about is more on a biochemical level not so disease based so these exogenous factors that are included right and and how our organisms and microorganisms are affected by the nutrients that we're supposed to be getting to feed them so they can feed us think about mitochondria mitochondria or bacteria we want to make sure we feed them properly so they can feed us so what is nutrition and genetics of course that's where we come up the topic of nutrigenetics this is a scientific study of how nutrition and nutritional supplementation affect our genetic variants so nutrigenomics is is new and upcoming age kind of medicine I don't think it is because we can find here that in 1975 there was actually a book written by Dr. Brennan where he discussed nutrigenetics and how using nutrition can help give us more energy so nutrigenetics kind of opens this conversation between you your practitioner or even just a lot of fitness people and stuff are getting into the you know the conversation of using genetics to see how you can train and the certain nutrients that you can use to kind of perform more optimally so this is also looking at the blueprint of how our micronutrients function in each and every one of us so being able to feed the right kind of nutrient into the cells so that these cells can work properly this was an interesting study that I found this was back in 2010 December 31st talks about nutrigenetics and nutrigenomics and how we can have this understanding of what nutrition actually means for our genetics right and how we can use different dietary things that to help influence our genetics in a really healthy way so nutrient interaction and actually designing particular lifestyles and and supplementation and also when it comes to the foods that we eat right so we can actually help kind of discuss the conversation of how are these genetic variants really going to affect us we know that lifestyle has a huge contributing factor to our genetic variants it's not doom and gloom and I don't want anyone to ever think that that just because you have this genetic predisposition that doesn't mean that you're obviously okay I'm predisposed to type two diabetes I'm gonna have type two diabetes absolutely not and just because you don't have the genetic variation doesn't mean that you're not gonna at some point have to worry about type two diabetes so I don't want anyone to get the wrong impression that I mean to just because you have this genetic variant that means you are doomed because that's actually not the case so what we're trying to figure out is is the metabolism the absorption and the use of these vitamins and minerals and how your biochemistry may not do that as efficiently as somebody else and how we can help support that so that you can thrive at a more optimal level which where the conversation gets interesting because most people I don't think understand the different types of genetic tests so I kind of broke them down into two separate categories we have your ancestry your carrier your trait and your pharmacogenetics all are super important the ancestry traits of course are looking more at ancestral origins are you Irish descent African-American English Scottish you know what is what is your descent and where do you come from and I actually think that's really cool to find out I have a patient of mine that says I have brown babies and I'm white and my husband's white where do these brown babies come from and I'm thinking hopefully not the mailman but we'll uh we can always look into genetic testing and find out what your what their origin is and we found out that they actually had cousins and stuff for that they were the same way they were brown children with white parents it was quite interesting uh the carrier status for different inherited type diseases uh like the bracket tests you know you're looking at colon cancer ovarian cancer breast cancer prostate cancer uh the so there are genetic tests that look into that as well uh disease based right so uh Alzheimer's Parkinson's type 2 diabetes are we predisposed to these drug and medication therapy I actually wish that more practitioners did look at this before prescribing medication right what kind of anti-depressant if the patient really needs this are they going to respond best to let's do some pharmacogenetics and find that out instead of playing the guessing game let's try Zoloft let's try Xanax let's try all these SSRIs SSRI and see what works best well the patient's sitting here kind of suffering going through this most of the time it is direct to consumer however there are practitioners that are using these genetic tests which is wonderful uh insurance companies are starting to look into this and I think that's the scary thing for a lot of people is that they have this understanding of this belief that the insurance company is going to see that their bracket test came back and they're predisposed for breast and ovarian cancer what does that mean if something like that happens down the road um so I think this is topic to actually absolutely discuss with your practitioner and look into with your insurance companies it also detects predispositions of particular diseases which I spoke of as well so some of these companies actually use your DNA for research and data outside of their software so make sure when you're looking at these consent forms and signing them that you're not signing your DNA this is the most personal data you have right so make sure you're not signing that away make sure that they're using it for their software only and not used unless you want them to absolutely so here's where nutrigenomics and nutrigenetics differs we're looking at more actionable snips right snips are single nucleotide polymorphisms these are genetic variants within your DNA whether mom just gave you this variant or dad or mom and dad did or neither did and that's what we're looking at um metabolic weaknesses where a weakness is within your biochemical pathway of being able to absorb use um and apply these specific nutrients that your body needs to thrive every day this is really not disease based even though we understand what each genetic variant means and what disease it could predispose you to we don't have that conversation with the patient we're mainly talking about things like your methylation uh your detoxification your neurotransmitters your immune inflammatory response those are the things that we're speaking of when we look at more of a nutrigenomic style versus a disease based um biochemical pathways which are super important to like like your methylation pathway so we're looking at your folic acid receptors your folate receptors your folenic acid your five-methe tetrahedra folate those are things that we're looking at not just oh you have the mthfr gene sorry uh that's a big scary thing and it's a big snip that a lot of people are hyped up about I guess is the word but we actually have figured out that we can use this to our advantage so nutritional support and nutritional supplementation guys this is nutrition and nutritional supplementation this isn't medications we're looking to see where we have these variants in these uh genetic predispositions of where we don't use these nutrients the way that we are supposed to when our bodies are less than optimal for how we want to perform so we're using nutrition and lifestyle and we're using nutritional supplementation to help these variants lifestyle recommendations yes so any kind of diet recommendations uh exercise recommendations these are things that we're looking at uh in nutrigenomics and nutrigenetics and then being mainly proactive and preventative we don't want to get it when it's too late I mean there's also some great cancer genetic testing as well on the other side here that that discuss and talk about different treatment forms based off of your cancer I mean I think that's really an amazing innovative advancement in science but we're looking to be more preventative and proactive Dr. Oz said it best genetics love the gun lifestyle pulls the trigger like I said this is not disease based and I'm not saying that your genetic predisposition is is is your determination by any means so of course I went to the fun institute for functional medicine I love this functional medicine model use it with all of my patients it just shows that we're not just looking at your genetic predisposition we are looking at so many different variants use this now so some of the things we're looking at of course is the patient story gosh I love listening to my patient stories right so talk to me about your life events I mean your first appointment with me is at least an hour long we're going over anything and everything that I can to find out more about you talk to me about your your family history what happened with your mom your dad your cousins your siblings your children what have they been predisposed to again lifestyle triggering events such as death in the family you lost a pet I mean these things can trigger our genetic variants in our enzymes to not work the way that they're supposed to so certain contributing factors of course mediators we're all we're looking at your your story tell me your story so some things that are modifiable and personal lifestyle factors of course things like sleep we know how important sleep is I want to know when you go to sleep I want to know when you wake up I want to know how you sleep I want to know if you have problems falling asleep or staying asleep all those are super important to understand exercise and movement how often do you exercise what type of exercise do you do because some people say I am exercising six days a week two hours a day that's a bit too much and I'm not seeing any results what's going on so understanding how they exercise and what they consider to be exercise is important also things like nutrition of course I want to know what you eat for breakfast lunch and dinner I also want to know what your favorite snacks are I'm going to ask you all these questions and you're super super nosy you work your stress level we all know stress is a predisposition for a lot of disease unfortunately or do you have highest level stress levels what are your contributing factors what do you do to relieve your stress those are some things that are important for me to understand a little bit more about you and also your relationships to me that's one of the biggest contributing factors to disease is toxic relationships whether it's work whether it's a relationship within the home whether it's a relationship with your children doesn't matter if you have a toxic relationship or involved with negative people that's going to bring you down so then we put it all together and we start looking at mental emotional and spiritual contributing factors right that's what we want to know so putting this all out filling it out literally for every single patient saying okay now let's break it down and now let's make it a little bit more easy for for me and for you as a patient to understand evolutionary mismatch right so when ancestral health that's what we talk about a lot is evolutionary mismatch so one of the terms that I've liked recently is is this term of functional foods right so these are things that have benefits beyond their basic nutritional functioning so what are these functional foods going to do for us and what are the best ones for us also nutritional anthropology right so this is the play between culture food and food systems that can affect our genetic variants it's not all about the genes so here's an interesting case of of evolutionary mismatch in my opinion current patient uh he's a 55 year old male his chief complaint is tiredness and fatigue I could be sitting at a meeting and I'm falling asleep I don't understand it I eat super healthy right he has low muscle tone this guy works out a lot lifts weights not just not just cardiovascular he's lifting weights and he cannot put on muscle mass he has been living a raw plant-based lifestyle for most of his life personal choice just thought that that was going to be better for him his genetic show poor methylation meaning he does not methylate his b vitamins very well and even in his labs show that he's uh his lab value for his b12 was under 500 and his RBC folate was also under 500 so he's definitely not getting b it b vitamins into the cells to be used by the body in his genetic variants they actually called me because they couldn't believe it this guy's 98 percent Neanderthal 98 percent I mean they have never seen that they called me because they couldn't believe it so here he is 98 percent Neanderthal and he's living a raw plant-based diet I said you're defying the laws of genetics and evolution what are you doing stop eating plant-based all the time right because studies show that Neanderthal was 80 percent animal protein and 20 percent plant sources a little imbalance there so no wonder he's not feeling well right and he's trying his best to get what he can from his foods but but it was difficult for him being raw plant-based by the way this is a somebody that I formulate for in Sun Warrior so I've tried really hard to get him to uh change his ways it's not working yet here's some unpublished research and data so I'll just give a little bit of the gist of this I wish I could tell you guys more and I can't wait it's pretty exciting this data has been accumulated for over 10 years we're looking at three plus generations we are using micronutrient testing 43 I believe essential of vitamins and minerals as well as genetic testing the participants in this study are within a very large community with similar genetic disorders kind of sort of might give it away so these people have a very small genetic pool but these are not people who are living the standard American diet either so this has been a really interesting study we have noticed that within just looking at their micronutrient supplementing them the way that they're supposed to and taking into consideration some of their genetic variants we've been able to decrease the risk of miscarriage and birth defects by more than 80 percent that's huge huge and of course the other thing is we want to optimize their overall health and wellness which is important so some of the things we've been doing nutrigenetics of course we're using to support the utilization of their foods and their supplementation lifestyle cofactors what do they do for a living we want to know that we want to help guide them when it comes to certain things that they're doing on a daily basis as well their exercise routine or lack thereof their soil nutrients so we can actually go in and say okay based off your geographical geographic location you have this missing from your soil so we're going to have you learn teach you how to garden how to put these nutrients back into your soil to grow your food because most of them do that so that way you can get the optimal amount of vitamins and minerals from your soil we are using essential micronutrient testing like i said about 43 of them we're looking at so that's b vitamins minerals you know different types of zinc copper folate b12 b6 b1 b2 b3 looking at all those variants to see where they're high and low also their genetic testing of course mostly we're doing a lot of them but mostly detoxification and anti-inflammatory snips how does their immune system work do they have an aggressive immune and inflammatory response and are they not able to detoxify the way that we would want them to from these certain toxins and chemicals which this group is is definitely less exposed to that too also personalized supplementation what do we get what do we give you what what kind of of b vitamin do we give you are you going to get folenic acid are you going to get five-method tetrahedra folate are you going to get 400 milligrams or are you going to get 800 micrograms i'm sorry micrograms so we can be that detailed not specific so personalized supplementation and lifestyle recommendations are also really important so what is the biggest threat to our dna it's not us right i mean it's not the fact that we're predisposed to these things that's our environment so what certain things in our environment do cause problems to our dna our work our work can be one of them right where do we work these industrial carcinogens that we're exposed to the exogenous estrogens that we're constantly exposed to heavy metals chemicals again occupation our water all those things are a part of what could change our genetic variants medications we are just so quick to take medications sometimes especially antibiotics my child has an ear infection here's an antibiotic a sore throat here's an antibiotic constantly taking antibiotics and most of the time when we were younger i know my mom didn't know any better so we were formulating this problem of antibiotic resistance as well which is not good because when we do need something we're not going to be able to find what we need to be able to take it so we can help these these bacteria that have no sudden and cause problems so medications can be a big problem as well and the overuse of them depleted soil so depleted soil with the loss of nutrients and minerals and micronutrients we want to make sure that are just like when we saw in this study that we're doing because of different geographic location we can actually see that we're missing a lot of nutrients from our soil and therefore we're not getting them just from eating our food like we wish we could and of course when it comes to toxic relationships stress depression anxiety life events this stuff happens we can't change that but if we can if it enhance the way or support the way that our bodies react to these things then at least when we go through these life stressors hopefully we can create more of a balance standard American diet yeah I hope nobody in here is eating like this I wouldn't think so but it happens and it happens more so but why because it's convenient and a lot of people don't know how to cook or don't know what to cook or don't know what to eat so they just go for convenience factor but it's making us all fat and sick right so of course the big question are we doomed is our genetics a doom and gloom or if we have these genetic variants is that it for us are we in trouble and I say absolutely not so neurogenetics is is the form of medicine that kind of lets us use it as a tool not a weapon we shouldn't be using this in the sense of oh you're predisposed to breast and ovarian cancer sorry be proactive get your screening done this and that but there's really no solution to that we want to use it as a tool to be able to help people be proactive and preventative and support their their lifestyle so we're actually starting to get into DNA custom nutrition and I know this is a this is kind of a new topic and we're actually having quite a lot of fun with it but looking into nutritional and nutritional supplementation so we're looking at what we call actionable genes or snips or variants and being able to see where in your biochemical pathway are you do you have a problem a hiccup I like to call it do you have a hiccup so we can come in and provide the right supplementation and the right nutrition for the right person at the right time and the right amount so what does that mean so when we're looking at let's just say methylation gene the mthfr most important it's definitely not the only one but it's it's the one that everybody knows the most about so when we're looking at that we can now say okay you're you're heterozygous in your mthfr both your 677 and your 1298 so that means you got a copy of this variant from one parent so when we see that we think okay we know we need to supplement with the five-method tetrahedra folate the active form of folate taking folic acid is not it's going to build up in the body because we don't know how to use it so now we understand that we can take per peer reviewed study and research we're looking at the different amounts and we've realized okay 400 micrograms and we're using lab testing to confirm this as well 400 micrograms of this quesropholic or five-method tetrahedra folate it's going to help get into the cell keep your homocysteine level where it's supposed to be and keep your folate your rbc folate level at a normal rate so that's what we're looking at so it's not so much i know everybody some people are kind of on the fence with this and and i was still kind of m2 sometimes but um now we can provide the right amount of nutrition uh to the right person at the right time should somebody take something in the am or should they take it in the p.m we don't think about those kind of things we just think i need to take my i need to take my supplements not what time and what you know what time and what uh what amount and am i going to take okay doctor said coq 10 so i go to the store and looking okay coq 10 you back when oh and you back when all what do i take i don't know i'll just take this one how much of it do i take well i don't know 800 milligram sure that sounds great um so we need to be able this is just allowing us to be more precise with our patients so that they're taking the right thing it's it's allowing for personalized medicine for optimal absorption again the evolution of dna based nutrition um the things i don't know how to use my thing um here on the left are talking about the things that we are looking at and on the right how we're actually able to support them so true life life events triggering events lifestyle okay we do need to take that into consideration and we do of course because it's not just your genetic variants that are important it's how you live your life what you do who you surround yourself with all that's important so we're able to um kind of give recommendations for optimal lifestyle choices for you will everybody follow that no but at least we know we can give them some options because if you start talking about disease and genetic predisposition disease sometimes they shut off and they turn away and they think i'm not going to uh you know stop eating this and exercise this way and i'm not going to start doing these things uh just because you say my dna says i should and that's true so we want to start talking about lifestyle sustainable lifestyle choices what's going to work for this person if i tell you to go home and meet bananas all day and you don't like bananas you're not going to do it so it needs to be sustainable also the propagation of disorder so the inability to resolve inflammatory and metabolic states uh which is your genetic component that we look at so we're now we're able to come in and help enhance your recovery potential everybody wants to see this downward spiral of genetics what we're doing is we're just throwing your rope and help pulling you out it doesn't mean it's going to change your genetic variance it just means that we're going to help support them molecular level interactions between nutrients and their bioavailability your micronutrients your lab testing those are important too we can't just leave that out and just look at the genetic component so now of course we're able to offer personalized nutrition and nutritional supplementation based not just only on your genetic variants but also your micronutrient testing and also the microorganisms and how they respond to our environment our ecosystem so we actually want to make sure that we can feed our bodies the right nutrients needed for us to thrive so to overcome genetic weaknesses now i do think we need to take into consideration the evolution of our nutrition and where it's gone and the things that we are we are our lifestyles our soils our our occupation our our relationships all those are super important when it comes to how our body is going to function because when we start having toxic relationships we're eating bad foods we're stressing out all the time we're not exercising i don't think that we're able to thrive we walk around functionally ill people forget what it's like to feel good so being able to bring in the discussion of hey yes here's some genetic predispositions based on biochemical pathways here are some lifestyle options that we can help offer you and here's some supplementation that we can help support those genetic weaknesses within those certain biochemical pathways to me it's just kind of helping a patient and a person be more proactive and preventative so that's it thank you okay so that was really amazing and i have to say that it's really given me some insight into how to try to make some have some idea about what to do when like how do you guess you know like it's not let's try not to guess let's try to see what we can do that's a little bit more precise so questions for jen please line up at the mic and so for you what do you think is the single most important if you had to do just one thing because a lot of people there's like all these recommendations but if you had to do just one what would you do oh just one thing out of everything all the stuff that you put up yeah just one thing oh see i'm not a one thing kind of lady either so that makes it difficult um honestly is is just to if it doesn't feel good don't do it stay away from your kryptonite foods that's a big thing everybody wants to they eat foods that take away your superpowers essentially and and don't don't eat those foods anymore i think food has a huge contributing factor to a lot of different disease and ailments i say this because if you thought about what the last person said it's kind of like i don't want to be overwhelmed i want to be able to take that first absolutely absolutely uh dr meyers helps me by person doctor so i'm gonna tell you about one of my experiences is i had a number of minor health problems and my genetic test showed that i can't eliminate histamines so i had an accident excess histamine problem well then that sent us on a quest to get rid of histamines either by food choices or supplements and it worked just it was amazing change so i'd say genetics show you where to look and what to do is up to what the doctor says oh no but it is true it just it's a blueprint it's a guide it just helps us it's not like i said it should never be the definite answer the only answer it should just be a guide to help us i got one more question and gene expression is how a gene works can you measure whether that gene expression is working correctly we can look at so for me it's a lot of symptomatic things that the patient tells me to so you got to listen to your patients they're going to tell you everything you need to know if you just sit there and listen to them that's why my first appointment second appointment third appointment is an hour along with these uh important people because i want to know more can we do blood test and measure certain things absolutely just because you have this vdr sniff this vitamin d receptor gene uh that says you have a hard time or a difficult time being able to absorb vitamin d it doesn't mean that you're vitamin d deficient by any means we need to check your blood levels and see and then we know how much to dose you with so we can tell if if it's affecting you to be able to measure if it's exactly turned on to me that's that's more symptomatic from the patient it's a great presentation thank you so if we talk about genetics being the blueprint the hardware the capabilities of your system and some folks are calling epigenetics the actual software that expresses those genes within the dna what role do you see with epigenetics in the work that you do so well i explain it to patients a lot of time is i always go back to car reference because people understand most people understand cars right so so what i do is when you buy a car you know what kind of gasoline to put into it you know what kind of oil you need uh because it tells you so this is kind of how i'm looking at things is what kind of nutrients need to go into your body and how much uh you know if you if you buy a let's go out you say you go out and buy a Porsche and you put diesel gas in it and it's not a diesel it may run but it's not going to run as efficiently as it's supposed to so this is just a really good guide for us to understand how your body works and how to put the proper nutrients in there so that you work uh at an optimal level i want you to be able to do everything you want to do in the day i don't care what that means if that means working four jobs and going home and being the best armed parent that you can meet your kids and then getting up at five in the morning and starting all over again i want you to be able to do that without feeling like you're constantly exhausted and get the most out of out of your day and out of your nutrients and out of your foods uh two quick questions one i'm actually working through a client with a similar case that's plant-based whole food right now they feel terrible but they're they're just trying to work through it what's like the first one or two steps to testing them to see what they're deficient in and kind of working them through that process yeah blood work for sure you want to check uh look at definitely with somebody who's plant-based you want to check their home is esteem levels uh you want to check their rbc folate a lot of people look at folic acid or folate but i like to look at the rbc folate you want to look at their vitamin b12 look at all their nutrients and see if they're deficient in it and if they are kind of help them in a way where they can take it i i understand i work for a robbing and protein company i get how hardcore these people are about what they do it's a lifestyle it's who they are it's a religion uh so i don't want to change that but we we can adapt what they eat and the things that they take uh to be more proactive and and to be able to drive that stuff into the cell so they can use it better i would say probably blood work would be the best and then of course nutrigenomic testing would be great because you can see if there's an issue within their methylation pathway uh which is going to make it it's going to make it challenging for a vegan yes but they can do it and they can supplement on top of their vegan diet you think absolutely absolutely i tell most of them that they absolutely need to and it's tough because when we do formulate for that we can't pull a lot of synthetics they don't want synthetics and so we have to find the natural sourcing for these vitamins and it can be done just tell them to go to sunwarrior.com and that dr gen formulates and i promise it's all good stuff but no i'm not trying to sell myself i promise sorry um but no they can supplement they should supplement in fact unfortunately most of us have to in some sense and second quick question you talked about environmental factors we spend you know a third of our life normally hopefully sleeping in our room do you recommend any kind of like air purifier or something for that environment that we're always in yeah make sure of course you're changing your air filters and such as well and and i know we're all guilty of this i mean i can't say that i'm not guilty of this make sure you shut if you have to have a tv in your room make sure you shut that off try to shut your tv off in fact they have switches where you can actually turn off the emf and you don't have to be so exposed to it but putting things putting those electronics away you know the little kids that sit there with that right in front of their faces and then they wonder why they don't sleep well so yeah it is important to make sure the air quality in the house is good changing the air filters actually in oriental medicine we say fans are bad exposes you to wind so you shouldn't sleep with a fan on but try telling a menopausal woman to not sleep with a fan on she's going to look at you like you're out of your mind so but yes you do need to to make sure that the home that you're in and that's a good point a lot of people don't consider is that we are constantly in our homes let's make sure that they're healthy environment for us that was a good point thank you thank you