 Alzheimer's disease, AD, is a devastating neurodegenerative disorder characterized by progressive memory loss and cognitive decline. Despite recent advances in understanding its underlying mechanisms, there remains no effective treatment to prevent or reverse the disease. Recent studies have focused on novel approaches to target the early stages of AD, including manipulating the immune system and enhancing autophagy. These strategies aim to reduce inflammation and preserve neurons, thereby delaying or even reversing the disease process. Additionally, lifestyle modifications such as dietary changes, physical activity, and mental exercises are being explored as potential interventions. With continued collaboration between scientists and clinicians, it is hoped that these efforts will lead to more effective treatments for AD. This article was authored by Allison B. Rice, Dahlia Mühidein, Berlin Jacob, and others.