 In this study, we examined the incidence of pressure injury among patients undergoing spinal surgery and identified potential risk factors. Our results suggest that the incidence of pressure injury is similar to that previously reported and occurs in the direct weight-bearing areas, leading to longer hospitalization. Additionally, we found that a lower preoperative serum protein level is significantly associated with intraoperative pressure injury occurrence during spinal surgery. This article was authored by Dae Hee Soo, Soo Yeon Kim, Byung Hoon Yoo, and others.