 Ghoshay disease is a rare genetic disorder caused by mutations in the GBA gene. It affects multiple organs including the bones, liver, spleen, and brain. Bone involvement is common in Ghoshay disease, causing deformities and limiting daily activities. In this study, researchers evaluated the principal radiographic findings in patients with Ghoshay disease. They found that the most common radiological feature was generalized rare affaction and enlarged narrow space in the jaws. Additionally, they observed anodontia or missing teeth in some cases. These findings suggest that the jaw is highly susceptible to bone damage from Ghoshay cells in the bone marrow. This article was authored by Giuseppe Minervini, Rocco Franco, Maria Maddalena Maripodi, and others.