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Blueberries: A Triple Threat Against Triple-Negative Breast Cancers

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Uploaded on May 3, 2010

City of Hope cancer center researchers and study authors Shiuan Chen, Ph.D., and Lynn Adams, Ph.D. discuss the results of a research study on the effects of blueberries on breast cancer.

Chen, research fellow Lynn S. Adams, Ph.D., and their colleagues applied blueberry extracts to TNBC cell cultures and found that blueberry extract not only inhibits proliferation and mobility in TNBC cells, it also led to cell death (apoptosis) at over twice the rate of untreated cells.

Chen, Adams and others then tested blueberry extracts effectiveness in laboratory animal models. The researchers found that the blueberry groups TNBC tumor weight was 70 percent lighter than the control group and it also exhibited significantly lower proliferation and higher apoptosis activity.

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City of Hope is a leading research and treatment center for cancer, diabetes and other life-threatening diseases. Designated as a comprehensive cancer center, the highest recognition bestowed by the National Cancer Institute, City of Hope is also a founding member of the National Comprehensive Cancer Network, with research and treatment protocols that advance care throughout the nation. City of Hope's main hospital is located in Duarte, Calif., just northeast of Los Angeles, with clinics throughout southern California. It is ranked as one of "America's Best Hospitals" in cancer by U.S. News & World Report. Founded in 1913, City of Hope is a pioneer in the fields of bone marrow transplantation and genetics. For more information, visit http://www.cityofhope.org.

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