 This research examined the etiology and pathophysiology of ventral hernias, focusing on the role of lipid peroxidation in the formation of the hernia. It was found that the presence of lipid peroxidation in the apnoerosis and muscle tissue correlates with the size of the hernia, suggesting that this process may be involved in the development of ventral hernias. Additionally, the content of free hydroxyproline in the blood was also found to correlate with the size of the hernia, indicating that the presence of connective tissue disorders may play a role in the development of ventral hernias. This article was authored by K. M. Kurbanov, H. C. Fakarov, and K. R. Nazarboev.