 Vitiligo is a skin condition characterized by patches of white or depigmented skin. It is believed to be caused by a combination of genetic and environmental factors, as well as autoimmunity. Neurovegetative disorders are associated with the degeneration of melanocytes, which can lead to vitiligo. These disorders include neurovegetative dysbiosis, which is a disturbance in the balance between the sympathetic and parasympathetic branches of the autonomic nervous system. Psychological reactions to having a cosmetic defect may also play a role in the development of vitiligo. This article was authored by R.A. Rakimov, K.M. Mukamedeva, and S.S. Ismatileva.