 Iskosweva is very important in this region, in the Eastern Central Africa region, to show how serious this disease is. It can cure up to 100% if there are particularly improved animals. It is estimated like about a million cattle die of this disease every year in this region. In situations where farmers keep one or two animals, they can completely wipe their livelihoods. In the more extensive farming systems, like the pastro systems, we find life so keepers lose like up to half of the calf population. The animals that survive from the disease, they are affected for life because of these cancer like effects. The animals do not grow as well as they could, they don't produce as much milk. So they are long term effects. Only two years ago, it was first reported in the Komoro Islands for the first time. So it's a 12th country in this region. Recently it's been moving very rapidly to the north of South Sudan. It is in the province neighboring Ethiopia and there is no reason why it cannot cross into that country. On the western side it's moved to the states bordering Central African Republic and there is no reason why it can't cross to that country as well. South Sudan and Central African Republic are going through some kind of civil war. I think East Coast fever would have a hugely devastating effect to the livelihoods of those people in those countries. It's a very effective vaccine and at the moment it's the only means we have to prevent the devastation from this disease. Even though it costs 8-12 dollars, there is a huge demand from all types of livestock keepers, both the small holders and the nomadic pastoral livestock keepers. So it's been very popular amongst the masses who have bought close to 600,000 doses over the last several years.