 This study demonstrated the effectiveness of a new artificial intelligence, AI, based system called the Prostate Cancer Artificial Intelligence Diagnostic System, PKADES, in predicting clinically significant prostate cancer, CSPCA. The AI system was able to accurately identify patients with CSPCA with high sensitivity and specificity, while reducing the number of unnecessary biopsies. This article was authored by Hui Yong-jong, Jin Ji, Jiu Liu, and others.