 This new method combines volumetric absorptive microsampling, the AMS, and the Emplex-Lew assay to accurately measure anti-influenza HA antibody levels in a single-fingistic sample. It also corrects the serum volume based on hemoglobin measurement, which improves accuracy and stability of the results. Furthermore, this method can be easily implemented in large population studies and clinical trials as it requires minimal training and is cost effective. This article was authored by Jiang Wang, Dong Meili, Alexander Wilts, and others.