 Granzyme K, GZMK, is a triptych member of the Granzyme family of chymotrypsin-like serine proteases produced by cells of the immune system that activates protease-activated receptor 1, PAR 1, and PAR 2, resulting in the release of inflammatory cytokines IL-6 and IL-8. This article was authored by Deon Kyserman, Paytian Zhao, Caitlin Lorraine Rowe, and others.