 23. Valent pneumococcal polysaccharide vaccine, PPSV-23, has been used in Hangzhou, China since 2003 as a private sector, vaccine chosen vaccine. The coverage of PPSV-23 among elders ranged from 0.17% to 0.69%, and the overall coverage was higher in urban areas than in rural and suburban areas. Most of PPSV-23 were used in children, while the proportion of the old population, over 60 years slightly increased over year. PPSV-23 was safe with a low reported AEFI rate, which was a little higher for children than for the elderly, over 60 years. This article was authored by Yang Yu, Yu Yang Xu, Zhang Wang, and others.