 VSP-1 is a selective autophagy receptor that can either promote or inhibit virus infections depending on the type of virus. It can target certain proteins involved in virus replication and prevent them from being used by the virus, thus reducing the severity of the infection. Additionally, VSP-1 can also target other proteins involved in virus suppression of RNA silencing, which can lead to increased resistance to virus infection. This article was authored by Xintong, Jiu Jiu Jiao, Wai Lan Feng, and others.