 Recent advances in rapid and affordable DNA sequencing technologies have revolutionized diagnostic microbiology and microbial surveillance. Availability of bioinformatics tools and online accessible databases has been a prerequisite for this. In this paper, we conducted a scientific literature review and presented a description of examples of available tools and databases for antimicrobial resistance, AMR, detection and provided future perspectives and recommendations. At least 47 freely accessible bioinformatics resources for detection of AMR determinants in DNA or amino acid sequence data have been developed to date. These include, among others but not limited to, ARGNOT, CARD, SRST2, MEGARS, GFinder, ARIBA, CMUR resistance, AMR Finder, and RES Finder. Bioinformatics resources differ for several parameters including type of accepted input data, presence slash absence of software for search within a database of AMR determinants that can be specific to a tool or clone from other resources, and for the search approach employed, which can be based on mapping or on alignment. Each tool has strengths and limitations and sensitivity and specificity. This article was authored by Rene S. Hendrickson, Valeria Bortalea, Heather Tate, and others. We are article.tv, links in the description below.