 The study evaluated the feasibility of recruiting and randomizing Medicare-certified nursing homes for a pragmatic cluster randomized trial comparing high-dose versus standard-dose influenza vaccine for their facility during the 2012-2013 influenza season, using minimum data set, MDS, 3.0 and vital status records for pre-specified clinical outcomes. The study randomized 39 nursing homes, coordinated vaccine delivery, implemented web-based data collection, and accessed MDS data, demonstrating feasibility. There were no differences in decline in functional status, but a lower adjusted relative risk of all-cause hospitalization, 0.680, 95% Ci, 0.537, 0.862, P equals 0.001 and NH mortality, 0.834, 95% Ci, 0.678, 1.027, P equals 0.087 in the high-dose group compared to the standard-dose group. This article was authored by Stefan Gravenstein, H. Edward Davidson, Lisa F. Hahn, and others. We are article.tv, links in the description below.