 Welcome to Fast Facts. MrBeast recently did a challenge video where you get $10,000 every day you stay in prison. In one part of the video, Josh, the participant, said that staying in there made him realize how precious time was and he spent the money on an engagement ring for his girlfriend. This made us really curious. What happens to your brain when you're stuck in solitary confinement? Besides the commonly known psychological side effects such as anxiety, suicidal thoughts, hallucinations, and depression, your physical brain also experiences drastic changes. There are three things that happen to your brain when you're in solitary confinement. 1. Sensory Deprivation This leads to your brain not releasing enough dopamine to seek out rewards. This is why someone in isolation can lose motivation. 2. The area of the brain that's responsible for learning, memory, and spatial awareness is called the hippocampus. When you're in solitary confinement, you're surrounded by walls with little to no visual or auditory stimuli. This lack of information leads to a decrease in hippocampus activity and it actually decreases the size of your hippocampus. 3. Another interesting thing that happens to your brain is the overactive amygdala. Your amygdala is the part of your brain that signals to you the feelings of fear and anxiety. The practice also affects physical health, increasing a person's risk of a range of conditions, including fractures, vision loss, and chronic pain. Do you guys want a video on when someone survives with no human interaction? Let us know!