 It's a given that vaccines prevent diseases and save countless lives. But would it take in 10 years or more to develop new vaccines? We need to find a faster way. One way to speed up the process is by making better use of human infection studies. Volunteers are given a sample of a vaccine under development, followed by a care for the monitoring infection. Medical care is always close to hand if volunteers fall ill. But if they stay well, it means the vaccine works, and can be made available much earlier. The idea is almost 300 years old, but using today's advanced technology, this type of study is not just scientifically sound by ethically responsible too, and of course, follow strict rules. Human infection studies show huge promise in the fight against diseases, like typhoid and malaria. But to develop vaccines most effective for people at risk of disease, we need to test them on those most at risk. By expanding human infection studies and targeting them better, the people most at risk of diseases could help develop the vaccines of the future and save millions more lives.