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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 3.7: Amperometric Sensors - Glucose Sensors I 00:24 Three types of sensors 03:00 A short history of sensors 03:49 A glucose sensor 04:58 Basics of a amperometric sensor 08:17 Glucose sensing 09:17 Why amperometric sensors? 11:52 Outline 11:59 Let us start with the cell on the left 12:12 Spontaneous reaction 13:48 Spontaneous reaction and the driving force 14:51 Driving a motor by chemical energy 17:19 Forced oxidation-reduction 20:27 Electrolysis: forced oxidation-reduction 22:18 Outline 22:20 The issue of reference electrode 23:07 Without a Reference Electrode ... 23:41 The purpose of reference electrode 24:12 A three electrode cell 24:34 Outline 24:37 Current proportional to H2O2 concentration 27:18 Validation of H2O2 response 28:57 Conclusion
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.