 This study demonstrated the potential of chamomile flour, olive leaf, and red tomato fruit extracts for the synthesis of zinc oxide nanoparticles, ZNONPs. The XRD results showed that the synth-sized ZNONPs had a dominant average size of 48.2 nanometers, which was similar to the size distribution analysis obtained from TEM. Additionally, the XRD patterns indicated that the synth-sized ZNONPs were pure crystalline shapes of ZNO. Furthermore, the antibacterial activity of ZNONPs synth-sized by Aaliyah Europia against Santhemona's Oryzi PV. Oryzi, Zu, strain GZ0003 was significantly higher than those synth-sized by Matricaria chamomila and Lycopacican esculentum. In conclusion, this study suggests that ZNONPs synth-sized by Aaliyah Europia have great potential for controlling bacteria-induced rice leaf blight disease.