 This study found that interstitial CD68-plus macrophages and CD8-plus T-lymphocytes had the strongest correlation with renal function at presentation in anti-neutrophil cytoplasmic antibody, ANCA, associated glomerulonephritis, AGN. Additionally, differences in the cellular infiltrate between focal and crescentic AAGN were related to CD68-plus macrophages and to interstitial MR-plus macrophages and T-lymphocytes. These findings suggest that the presence of these cells may play a role in the pathogenesis of AAGN. This article was authored by Dana Kitter, Susan E. Bray and Stuart Fleming.