 This paper examined the relationship between plasma concentrations of DMT and its effects on the brain. It found that DMT suppressed alpha power, increased beta power, and increased Lempel Ziv complexity. Additionally, it showed that there was significant between subject variability in the EC50e, concentration needed to reach half of the maximum response for each effect. This suggests that the effects of DMT are highly dependent on individual differences in the subject's physiological state. This article was authored by Emma Ekernaz, Christopher Timmerman, Robin Carhart-Harris, and others.