 This study examined the effects of various factors on the mental health of Portuguese healthcare workers during the first wave of the COVID-19 pandemic. The results showed high levels of burnout, stress, depression and anxiety, with 55% of participants reporting high levels of personal burnout, 55.1% reporting high levels of work related burnout, and 35.4% reporting high levels of client-related burnout. Additionally, 28.7% of participants reported moderate to high levels of depression, 36.4% reported moderate to high levels of stress, and 33.1% reported moderate to high levels of anxiety. Furthermore, 78.3% of participants displayed moderate to high levels of resilience, while 1202 participants, 78.3%, demonstrated moderate to high levels of satisfaction with life. The study concluded that governments and hospital administrations should take action to promote resilience and satisfaction with life as these variables are protective relating to mental health problems. This article was authored by Andrea Teixeira, Ivan Duarte, Rita Pinu, and others. We are article.tv, links in the description below.