 The COVID-19 pandemic has had a significant impact on antimicrobial resistance, AMR. Short-term effects include reduced antibiotic use in high-income countries due to increased awareness of hand hygiene and decreased mobility. Longer-term effects may include the spread of AMR through overuse of antibiotics in COVID-19 patients, shortages of personal protective equipment and lack of qualified healthcare staff. Despite these challenges, there are some positive developments that can help reduce the spread of AMR, including increased public awareness of infectious diseases and infection control, the strengthening of the One Health approach and the formation of international research collaborations and platforms. This article was authored by Marco Senagini, Susan Rufnacht, Baharak Babi Fluri, and others.