 And one of the interesting stories is Manuel Guzman and his research team in Spain were looking at brain cell metabolism and they knew that THC had been found to work with receptors in the brain so they were curious how THC affected brain cell metabolism. The studies they were doing were done with brain cancer cells because they reproduced really quickly and you can have a line of cells to study without having to keep buying normal cells. You have your own dedicated line reproducing really quickly and it's much cheaper than buying them and you can get basically the same data. So when they started trying to research THC with brain cancer cells, they couldn't do the research because all the brain cancer cells died off. What's this about? They tried again. Brain cancer cells died off. Complete death. So they said, wait, wait, wait, wait. They went to the literature. They found the study from 75, so that gave them a clue that what they were seeing was valid and they redirected their study away from brain cell metabolism into cancer, brain cell cancer and how cannabinoids affected and they found that THC and synthetic cannabinoids have the ability to change the signaling at a genetic level so that the cancer cells change their biochemistry. Instead of making pro-survival chemicals within the cancer cell, the genetics are flipped so that they start making chemicals that are hostile to their survival and then they die off. Another thing that the cannabinoids do is to impede the ability of tumor cells to produce blood vessels. In order to eat because they divide rapidly, they need a lot of nourishment. That's why cancer patients waste. These tumors tap into the host and suck the blood. They're vampires. They tap into the blood system and draw off nutrients. THC inhibits the ability of the cancer tumor cells to produce a compound necessary for producing these blood vessels. This inhibits their ability to thrive and to spread and once they spread to get a doc and to survive as a metastasis. They were really amazed by this and continued their research. Once they published, other researchers started looking at it. They found similar activity for breast cancer cells, for colon cancer cells, for head and neck cancer cells, bile duct cancer cells, pancreatic cancer cells. So many different lines of cancer cells all responded to THC or synthetic cannabinoids that activate these receptors.