 The study evaluates the impact of great vine rootstocks on the growth and tolerance of new grape cultivars to stress factors like drought, in regions where supplemental irrigation is more frequently needed due to climate change. The experiment was conducted on two-year-old soilless grown Primavines grafted on nine rootstocks, with a long-term deficit irrigation, DI, imposed before bud break. The results show that the 140-rewe rootstock significantly mitigated the adverse effect of water deficit on the physiology and growth of the cyan genotype Prima, and that V. Berlandieri times V. Rapestris pedigree rootstocks generally performed better than others. This article was authored by Alper Cucabas-Masai and Ali Sabir.