 This paper discusses the use of high-frequency piezoelectric crystals, HFFQCM, for detecting DNA molecules using a self-assembled monolayer, SAM, technique. The SAM technique was used to verify the presence of DNA on the crystal surface by analyzing the crystal's infrared absorption spectrum. The crystal's phase then changed when DNA was added, indicating successful immobilization of the DNA. The amount of DNA present on the crystal was also measured and found to be proportional to the amount of DNA added. Finally, the authors observed a saturation point at which no more DNA could be detected, suggesting that the crystal had reached its maximum capacity. This article was authored by Camillo Ortiz-Monsalve, Jorge Mario Guerriganzales, and Marisol Jaramillo-Brajales.