 Male patients with lupus nephritis, LN, tend to present with more severe forms of the condition than their female counterparts. They also have a higher risk of developing rapidly progressive glomerulonephritis, RPGN, and low serum complement levels. Additionally, males are more likely to experience symptoms such as asymptomatic hematuria and or proteinuria, while females are more likely to present with mild symptoms. Despite these differences, male patients with LN do not appear to have worse long-term prognosis than females. This article was authored by Nansing Pan, Bhattana Chawana Suntrapaj, and Bhunirit Chhinsakan.