 of 14 million new cancer cases in 2012, 2.2 million, 15.4% were attributable to carcinogenic infections. Helicobacter pylori, human papilloma virus, hepatitis B virus, hepatitis C virus and Epstein-Barr virus were the most important infectious agents worldwide. Caposis succoma was the second largest contributor to the cancer burden in sub-Saharan Africa. This article was authored by Dr Martin Plummer, Ph.D., Kaffirinda Martell, N.D., Jerome Vignette, Master of Science, and others.