 The recent revisions to the federal policy for the protection of human subjects require that informed consent documents include a concise and focused presentation of key information. This includes organizing and presenting the information in a manner that facilitates comprehension. However, there is no specific guidance on what information should be included or how it should be presented. To address this gap, we conducted a review of randomly selected key information templates from 46 US medical institutions to assess how they are implementing the new regulations. Our findings suggest that most institutions are providing clear and concise summaries of key information, but some are still struggling to provide a more user-friendly format. This article was authored by Jessica Mazurski, Matthew P. Robluski, Erin D. Solomon, and others.