 The caduceus trial showed that injecting cardiosphere-derived cells, CDCs, into damaged heart tissue can help prepare the damage and restore function. These cells release exosomes, which contain specific molecules that can protect the heart from further injury and promote healing. Researchers found that these exosomes also contained certain microRNA molecules, including MIR-146A, which can replicate the beneficial effects of CDCs on the heart. This suggests that MIR-146A could potentially be used as a treatment for heart disease. This article was authored by Ahmed Gamal El-Din Ibrahim, Kucheng, and Eduardo Marban.