 Periodontal diseases are inflammatory conditions caused by certain types of bacteria found in the mouth. These bacteria can cause damage to the gums, leading to gingivitis, and if left untreated, can progress to more serious forms of periodontitis. Inate immunity is the body's first line of defense against foreign invaders, while adaptive immunity involves the production of antibodies and other proteins to fight off the bacteria. Cytokines produced by both innate and adaptive immunity play a role in the progression of periodontal disease. Osteoblasts and osteoclasts work together to maintain skeletal health, but when the balance is disrupted, it can lead to bone loss and eventual tooth loss. Endocrine and immune systems interact to control this balance, and inflammation from periodontal disease can affect the endocrine system and increase risk of other chronic diseases. This article was authored by Nora Silva, Loretto Abuslim, Denise Bravo, and others. We are article.tv, links in the description below.