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Uploaded on Jun 12, 2018
A movie showing the three-dimensional structures and interactions for three proteins in the human nuclear pore complex — a gatekeeper in the cell that ushers mRNA molecules from the nucleus to the cytoplasm. Gle1, which is stabilized by Nup42, helps activate DDX19, priming it to bind mRNA molecules. Ultimately, DDX19 helps to send mRNAs along their way, so that they can be translated into proteins in the cytoplasm.