 FAPESA3 is a novel two-dimensional nanomaterial that can be used as a photothermal chemodynamic agent for cancer treatment. It contains iron and phosphorus, and it has been shown to produce a powerful photoacoustic signal when exposed to light. Additionally, this material can be used as a magnetic resonance imaging, MRI, and photoacoustic imaging, PAI, agent because of its composition of iron and the previously discovered PA signal. Furthermore, FAPESA3 can be loaded with anti-PD1 peptide, AP, which is then encapsulated within a CT26 cancer cell membrane, CCM. This combination of materials is called FAPESA3 at AP at CCM, and it is capable of both photothermal therapy and immunotherapy against cancer. When exposed to near-infrared laser light, FAPESA3 at AP at CCM causes highly effective tumor ablation while also triggering immune responses. In addition, AP blocks the PD1-PD-L1 pathway, allowing cytotoxic T-cells to be activated, resulting in stronger anti-cancer immunity. Finally, this article was authored by Xu Yanfeng, Xianlin Wu, Zhendomli, and others. We are article.tv, links in the description below.