 genistine has been shown to be effective in reducing the severity of gastric ulcers in rats. This is due to its ability to decrease the expression of WNT, ketinin, TGF, SMAD4, and PKB, all of which are involved in the development of gastric fibrosis. This article was authored by Hernan M. Hassan, Nuf M. Alatawi, Olober Gallagel, and others.