 This study aimed to investigate the role of entero-toxigenic Escherichia coli, ETEc, Clostridium difficile or Clostridium perfringence type C in the etiology of neonatal piglet diarrhea in Greece, and to identify preventative measures against these pathogens. A total of 78 pooled feces samples were collected randomly from 234 suckling piglets aged one to four days old from 26 farms. The collected samples were first screened for the presence of E, coli and C, difficile or C, perfringence using culture methods on macconky and anaerobic blood agar plates, respectively. Of the samples tested, 69.23% were positive for ETEc strains, 30.77% were positive for ETEc strains containing the F4 entero-toxin, 61.54% were positive for ETEc strains containing the F5 entero-toxin, 42.31% were positive for both ETEc and E, coli entero-toxin LT. This article was authored by Nikolaos Takoras, Eleftherios Miletus, Polychronis Castillas, and others. We are article.tv, links in the description below.