 Inflammation is considered to be a major cause of most chronic diseases, especially in more than 100 types of inflammatory diseases. TBK1 is a serine-thraining protein kinase which regulates antiviral defense, host virus interaction, and immunity. It is ubiquitously expressed in mouse stomach, colon, thymus, and liver. This article was authored by Daoyu, Yang Suyi, Yang Yang Yang, and others.