 The objective of this study was to compare the effectiveness of health education as an intervention to promote breast self-examination, BSE, among intervention and non-intervention group presenting in a low-resource setting at North Karachi. Methodology, this quasi-experimental study was conducted from January-August 2018 in a charitable hospital in Karachi after taking ethical approval by the institutional review board of Jinnah-Sindh Medical University and relevant approvals from the hospital authorities. This study recruited 172 eligible women by dividing them into Intervention, N equals 86, and Control, N equals 86, groups from a low-resource setting in Karachi. Demographic variables were collected through pre-tested questionnaire by interview. Intervention group then received health education regarding carcinoma of breast, importance of BSE, and monthly motivation to perform BSE through cell phone. The questionnaire was again filled after six months of intervention. Control group was also given health education sessions upon completion of study. Results, results revealed that both groups were similar initially. After six months females in intervention group showed significant, P equals 0.0. This article was authored by Zora Jibin, Naya Chah, Zima Amr, and others. We are article.tv, links in the description below.