 Microfluidic mixing has been shown to be an effective way to create lipid nanoparticle, LNP, CERNA systems with high encapsulation efficiency and low polydispersity index. This technique allows for precise control of the mixing process, making it suitable for large-scale production of LNPs. Furthermore, this method produces LNPs with a smaller size distribution than current methods, allowing for more efficient delivery of CERNA into cells. This article was authored by Nathan Embelevo, Jens Hufft, Paolo J. C. Lin and others.