 the immune system plays a crucial role in protecting against cancerous growths. However, tumor cells have evolved strategies to avoid detection and destruction by the immune system. These include evading recognition by T-cells through alterations in peptids presented on MHC molecules or by secreting cytokines that suppress T-cell activity. Additionally, tumor cells may induce the production of regulatory T-cells, tregs, that suppress anti-tumor responses. Furthermore, tumor cells can also secrete factors that cause immunosuppressive conditions, leading to a state of immunodeficiency. Finally, tumor cells can escape from the immune system by developing resistance to immune checkpoints, allowing them to continue growing unchecked. To counter these strategies, researchers are investigating ways to boost the immune system's ability to recognize and destroy tumor cells. This article was authored by Katrin Topfer, Stephanie Kemp, Nodya Muller, and others.