 This systematic review found that there is a lack of robust research to inform policy on the barriers to quality cancer care in sub-Saharan African, SSA, countries. Most research has been conducted in only a few countries, focusing primarily on breast and cervical cancers. Additionally, the majority of research output is from Nigeria and Ethiopia, which may not be representative of the entire region. Furthermore, the research has shown that many of the barriers to quality cancer care in SSA include high costs of diagnostic and treatment services, lack of coordination between primary, secondary, and tertiary healthcare sectors, inadequate staffing, and continued reliance on traditional healers and complementary medicines. This article was offered by Ajay Agawal, Janet Seely, Amos De Gracius Moaka, and others.