 Bone tissue engineering is a rapidly growing field that combines multiple disciplines including material science, mechanical engineering, clinical medicine, and genetics. The goal is to restore and improve the function of damaged bones through the use of scaffolding materials that provide a suitable environment for tissue regeneration and repair. Materials and manufacturing technologies have been developed to mimic the natural biological neighborhood as closely as possible. These include combinations of cells and matrices made from various types of materials. This review provides an overview of current materials and manufacturing technologies for bone tissue regeneration. This article was authored by Petra Chakalata, Blastimil Kulda, and Voslaw Babuska.