 Resveratrol, a polyphenol with antioxidant, anti-inflammatory, anti-proliferative and anti-angiogenic effects, has been studied for its potential role in various diseases due to its beneficial effects on oxidative stress. The main focus of this review is on the signaling pathways affected by resveratrol, particularly in cardiovascular diseases, cancer, neurodegenerative diseases, and longevity. This article was authored by Batouli Kattelgall, Semi-Batteral, Yavuzi Taga, and others.