 The study examined the effects of a mutant gene called 3E182G which causes a decrease in the amount of glutamate binding to the GABA protein. This mutation leads to a reduction in the ability of glutamate to enhance the activity of the GABA protein, resulting in a decrease in the overall level of inhibition in the brain. This decrease in inhibition can lead to increased levels of excitability in the brain, leading to increased risk of seizure and other neurological disorders. Furthermore, the study also showed that overexpressing the wild type 3 subunit of the GABA protein could restore the normal level of inhibition and reverse the behavioral changes caused by the mutation. This article was authored by Yerong Du, Junxia Li, Mao Jiu Wang and others.