 When you're, you know, urinating, you're having toxins come out. Well, those toxins have to be basically collected in one place before they're evacuated into the toilet, and that's your bladder. So over years and decades, those toxins that you're urinating out start to accumulate in the bladder, which is why smoking, for example, is definitely linked to bladder cancer. Immune therapy came out relatively recently, which does improve bladder cancer and can qualify for people that cannot tolerate chemotherapy. Finally, it's happened to where now we have actionable and targetable mutations that we can do with an oral pill to help control disease. Now it doesn't just have to be stage 4 metastatic. The key term is muscle invasive bladder cancer. That's the key. Every biopsy report should say is it muscle invasive? Is it non-invasive? If it says no muscle present, the recommendations are to go back in biopsy because that is the key.