 The study aimed to identify the profile of circulating C19MC microRNAs in patients with established preeclampsia, fetal growth restriction, and gestational hypertension, and examine their correlation with disease severity and clinical signs. Increased extracellular levels of MIR 516-5B, MIR 517, MIR 520A, MIR 525, and MIR 526 were detected in patients with preeclampsia, but no relationship was found between C19MC microRNA-plasmatic concentrations and expression profile and identified risk factors for a poorer perinatal outcome. The study also demonstrated the dependence between the levels of plasmatic C19MC microRNAs and the pulsatility index in the middle cerebral artery and the values of cerebral placental ratio. The upregulation of MIR 516-5B, MIR 517, MIR 528, MIR 525, and MIR 526A is a characteristic phenomenon of established preeclampsia. This article was authored by Ilona Romadnikova, Katerina Kotlobova, Marteta Ondrakova, and others. We are article.tv, links in the description below.