 This systematic review aims to evaluate the methodological quality and overall level of evidence of diabetes PROMs, categorizing them based on outcome measures assessed. A total of 363 articles were identified, with 238 unique PROMs validated in the type 2 diabetes population. The CPDQ, DSMI-20, and CIT-ASHK are among the PROMs with a moderate level of evidence for greater than or equal to five measurement properties. These findings may assist clinicians and researchers in selecting appropriate high-quality PROMs for clinical practice and research. This article was authored by Priscilla Jialing-Wi, Yuheng Kwan, Dian Hui-Fong Lo, and others.