 The Swiss Personalized Health Network is a federal initiative aiming to bring Switzerland at the forefront of personalized health research. Our goal is to create a technology and policy environment in which health-related information becomes interoperable between scientific disciplines as well as across institutions. And this will allow in the end researchers, both in the clinical environment and in basic research and in bioinformatics to analyze the data seamlessly and to contribute to advances in health care and precision medicine in the future. The SIB Swiss Institute of Bioinformatics will mainly contribute in two functions. The first one is establishing a network of secure, protected IT infrastructure environment which allows scientists to work with patient data without disclosing their privacy or compromising security. And the second contribution is on data interoperability in the form of the data coordination center. And by data interoperability we mean that information that is generated at one side or at one discipline must become comparable with information that is generated somewhere else. And this starts with simple things like the format in which the data is stored and ends with very complicated things like what is the semantics? What is the meaning of the different terms in the various contexts? And we have to bring them together such that we can combine information and analyze them in a common new. SIB has many years of experience in managing and safeguarding biological information for the community. We have experience in clinical bioinformatics both on a European and a Swiss scale. And by our federated structure the SIB has been for many years a trusted partner of Swiss universities and hospitals in providing scientific services because it's not linked to an individual institution but it serves the scientific community as a whole.