 Tämä on se, miten se on tehty tänään. Täältä oma hämme. Täältä oma hämme. Täältä oma hämme. Can you imagine, or do you know, how it feels? It hurts. 8.5 % of world population is suffering diabetes. And the number is increasing. This means that big part of us is injecting insulin every day. The good news is that we have insulin. Insulin is a peptide hormone. And peptides are very good drugs with low toxicity. But they degrade in stomach. Which means that we cannot take them as a pill, but we need these old-fashioned injections. Skin consists of several layers. And in order to penetrate them all, we need quite a long needle. This needle is hitting the nerves and causing the pain. And the pain decreases people's willingness to take the medicine. So we don't want to change the drug. But maybe we can change the way to deliver it. And my idea is to use poros, silicon, nano needles. These nano needles would penetrate only the outermost layer of the skin. Which actually is the most effective barrier. But they do not cause pain. They would be poros so that we can load the drug inside the needle before the use. And actual use would be as simple as applying a blaster. In addition we are using silicon. Which means that we can have electrical control to the system. And maybe in future we can have the sensing also to the same device. I have research plan ready. In University of Turku we have excellent and unique facilities for making poros biomaterials. In addition we know how the surface charge affects the peptide loading and release. I have already contacted a collaborator in London and he is very willing to help me with this project. I would love to go there to make these needles because they have top notch micro fabrication facilities and they can help me to test these needles in living system. So I want to take the pain away from peptide injections. I have everything ready. And in order to show that this can work only the funding is needed. So what if instead of long needle we had this. Thank you. That was awesome. Perfect. So just before we go over to the judges. Which remind the audience actually the judging criteria they are really looking for here. So for the scholar award they are looking for the most novel, scientifically ambitious and society relevant ideas. And of course how well they've pitched and communicated here today. So over to the judges. Guys please ask questions. Mari. Thank you Martin very much for the good presentation. I would like to ask that how are the IPRs of these needles than if you have collaborator in London. So have you been thinking that how to protect this? Yes we've been thinking about it a little bit and in London they have some IPRs processes going on but we are not quite there yet. So we need to study it a little bit more and meanwhile do the IPR processing also. Great. Then Vince you have a question. I was wondering how is the drug loaded on these needles and whether or not you are thinking about the storage place for the drug in the silicone micro needles. How do you load the drug there? So the idea there is that there is a film we can make Poro's film on below those needles also. So we can load the drug there and there is a lot of Poro's volume. So empty volume basically inside those needles what we can use. And we just put from the solution we put the peptide inside the needles. I actually had quite similar question. We actually invested in a company out of University of Waterloo that's commercializing micro needles and I think, I'm not sure if it's, where the true difference is actually that's using patches for testing biomarkers from the interstitial fluid in the skin. So I understand the taking out something from the skin just because of the physics of it, because of the capillary. But I don't understand how you push something in there because of how you put something in the blood. How you actually put, does it make sense? And also second question, I'll just use my time. We have to move on. We can talk later. Thank you so much.