 Welcome back to our meds smarter lecture series where we're taking a smarter approach to preparing future physician Before we get started if you'll take just a quick minute and click that like button and also Subscribe and turn the bell on so that you'll be notified when we post new videos Let's continue on and discuss Listeria monocytogenes. This is a gram-positive facultative Cellular rod and remember facultative means that it's able to live either within or out of a Host cell you get this infection by ingesting the unpasteurized dairy products or cold deli meats And it can cross over the placenta. So it's a trans placental transmission So what that means is that you can pass this on to a child during childbirth By vaginal transmission there. Listeria does grow well at refrigeration temps So this is why we always tell pregnant women to avoid things like deli meats or unpasteurized dairy foods Because of the potential for them to become infected with Listeria that could then pass it on to their child It forms what are called rocket tails via actin polymerization and these rocket tails are actually what give it its tumbling Motility and a broth and it allows the intracellular movement and cell-to-cell spread across membranes This also helps it avoid antibodies that can come in and deactivate this To treat it. It's fairly simple to treat. We use ampicillin However, it is more difficult in the baby than it is with a mother some things that Listeria can cause is Amneonitis septicemia and spontaneous abortion in our pregnant women. So once again, this is why we Suggest not to eat deli meats for ladies that are pregnant. It can also cause granulomatosis Infantis septica and basically this is a infection an intrauterine infection. It is highly fatal for the Fetus however, it is not very fatal for the mother another infection for those that are immunocompromised can be meningitis Especially for those that are neonates or older adults that have an immunocompromised state But finally those that are healthy people. They really only have kind of gastroenteritis. It's real mild There's real no problems with it and you know like we said you can use ampicillin to treat it of note this picture here is a scanning electron micrograph of the Listeria if you found this material helpful for your studying Please like and consider subscribing to the channel also share this video so that more people can benefit from it like you have